HbA1c and Serum Level of VEGF in Diabetic Retinopathy Patients

Objective: This study aims to determine whether HbA1c level has a correlation with vascular endothelial growthfactor (VEGF) serum in diabetic retinopathy (DR) patients.Methods: is an analytical cross-sectional of patients DR due type 2 diabetes, purposivesampling technique. Patients were grouped into non-proliferative (NPDR) and proliferative (PDR). HbA1cand VEGF levels assessed by taking the patient’s venous blood.Results: A total 82 samples included, which mean 8.17% ± 1.91% medianVEGF 85.78 ng/L (range 38.23-149.43 ng/L). 23 out 35 NPDR female (65.7%),while 29 47 PDR male (61.7%). Approximately 61.7% had DM duration ofmore than 10 years, while 62.9% less years. There was increasein group compared NPDR, although it not statistically significant (p =0.214), there no difference median two groups. Spearman’s analysisrevealed between HbA1 retinopathy, both PDRgroups (correlation coefficient 0.183 -0.022 respectively).Conclusion: No found diabeticretinopathy patients. In this poor glycemic control proven for their implications VEGFprogression. may be used as marker severity.